Benzyl Alcohol (Dosing, Interaction, Side Effect, Administration, Etc..)

CLASS:
Anesthetic, Local
Pediculicide

DOSING:
Adult Dose:
Pediculosis capitis:
Apply sufficient lotion to dry hair to completely saturate the scalp and hair; leave on for 10 min; then rinse off thoroughly with water; repeat treatment after 7 days

Pediatric Dose:
General Dosage Information:
Safety in pediatric patients below the age of 6 months has not been established

Pediculosis capitis:
(6 months of age or older)
Apply sufficient lotion to dry hair to completely saturate the scalp and hair; leave on for 10 min; then rinse off thoroughly with water; repeat treatment after 7 days

INDICATIONS:
FDA-LABELED INDICATIONS:
Pediculosis capitis

ADVERSE EFFECT:
Common:
Dermatologic:
Erythema (10%)
Pruritus (12%)
Pyoderma (7%)

Ophthalmic:
Eye irritation (6%)

CONTRAINDICATION:
Specific contraindications have not been determined

PRECAUTION:
Neonates (less than 1 month of age) or preterm infants (corrected age less than 44 weeks); increased risk for neonatal gasping syndrome; use not recommended
Pediatric patients under 6 months of age; use not recommended due to potential for increased systemic absorption

PREGNANCY CATEGORY:
B (FDA)

BREAST FEEDING:
Infant risk cannot be ruled out.

HOW TO TAKE OR ADMINISTRATION:
Topical:
Avoid contact with eyes by keeping eyes closed and covering with a towel
Apply directly to dry hair covering entire scalp and all scalp hair
Massage into hair and scalp; be sure to apply to the area behind ears
Dripping will occur when head is completely saturated, be sure to protect eyes and skin from these drips

DOSAGE FORM:
Topical Lotion:
5 %

TREATMENTS:
MANAGEMENT OF MILD TO MODERATE TOXICITY:
Treatment is symptomatic and supportive.

MANAGEMENT OF SEVERE TOXICITY:
Treatment is symptomatic and supportive. Neonatal gasping syndrome has been reported in patients receiving IV products containing

benzyl alcohol

. Treat hypotension with IV fluids and pressors if needed. Treat seizures with benzodiazepines; barbiturates or propofol may be needed if seizures persist or recur. Severe metabolic acidosis (arterial pH less than 7.1) should be corrected with IV sodium bicarbonate (a reasonable starting dose is 1 to 2 mEq/kg).

TOXICOLOGY:
TOXICITY: Deaths in neonates were associated with administration of 99 to 234 mg/kg/day in large volume parenteral solutions or endotracheal solutions. Rectal administration of 45 mL was reportedly fatal. Severe toxicity has not been reported after ingestion or dermal application.




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For the Registered Medical Practitioner Only. We are not recommended for self medication. self medication is may harmful for health. We are only Provide information about medicine.